Department of Biochemistry, Sharma University of Health Sciences, India
Original Article
Gender Based Changes in Cord Blood Heme Oxygenase-1
Author(s):
Kharb S*
Evidences support the role for the heme oxygenase system (HO-1) in the maintenance of a healthy pregnancy, especially during pathological challenge. To study gender-based changes in HO-1 levels in cord blood by comparing the concentrations of heme oxygenase-1 in maternal and cord blood venous sample of normotensive pregnant and preeclamptic women. Fifty pregnant women were selected and grouped as group 1 (control, n=25) comprising of normotensive women immediately after delivery; Group 2 (study group, n=25) comprising of age-and sex-matched preeclamptic women. Study samples were drawn (maternal venous blood and umbilical cord blood) and heme oxygenase-1 was analyzed by competitive enzyme linked immunosorbent assay. There was significant rise in serum heme oxygenase 1 levels in preeclamptic women as compared to normotensive pregnant women (p<0.001). Cord blood hemeoxygenase-1 levels.. Read More»
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