School of Women’s and Children’s Health, Royal Hospital for Women, University of New South Wales, NSW, Australia
Research Article
Nerve and Blood Vessel Wiring in Endometriotic Peritoneal Lesions
Author(s):
Frank Manconi*, Yingying Su, Robert Markham and Ian S Fraser
Detection of unique nerve fibres in the endometrium of women with endometriosis and subsequently in their peritoneal lesions has led to increased interest in studying their relationship with infertility and pain. Blood vessels and nerves fibres course throughout the body in an orderly pattern, often alongside one another. Although superficially distinct, the mechanisms involved in wiring neural and vascular networks seem to share similarities. We found that nerve fibres and blood vessels traverse the endometriotic peritoneal tissue in slightly different ways with variations in length densities (Lv), branch point density (Bv), segment length between branch points (Lv/Bv) and capillary radial diffusion distance r(diff). The capillary radial diffusion distance r(diff) and the spatial co-localisation distance in conjunction with nerve fibres fell within range for the facilitation of the p.. Read More»
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